Establishing an Integrated Multidisciplinary Workflow for Early Detection and Management of Drug-Induced Organ Toxicity: Leveraging Laboratory Biomarkers to Enhance Collaborative Roles of Pharmacists, Nurses, and Clinical Diagnostics

Abstract

Background: Drug-induced organ toxicity (DIOT) is a critical challenge in modern healthcare, leading to significant morbidity and mortality. Timely detection and management are essential to mitigate its effects, yet current workflows are often fragmented, delaying interventions. Laboratory biomarkers offer a promising avenue for early detection, enabling precise, patient-centered interventions.

Aim: This paper aims to establish a multidisciplinary workflow integrating laboratory biomarkers into DIOT management, emphasizing the collaborative roles of pharmacists, nurses, and clinical diagnostics to improve outcomes.

Methods: The study employs a structured review of existing literature and primary data collection from healthcare settings adopting biomarker-based DIOT workflows. Key performance indicators include biomarker sensitivity, interdisciplinary collaboration, and patient outcomes. Findings are analyzed to design and validate a comprehensive framework.

Results: Preliminary findings demonstrate that integrating biomarkers improves the timeliness and accuracy of DIOT detection. Collaborative workflows enhance communication between pharmacists, nurses, and laboratory professionals, leading to more efficient care pathways and reduced organ damage. Patient outcomes show significant improvement, with reduced hospitalization rates and better long-term prognosis.

Conclusion: Establishing a biomarker-driven, multidisciplinary workflow addresses critical gaps in DIOT management. The framework not only improves early detection but also fosters effective collaboration, laying the groundwork for scalable healthcare solutions to combat DIOT globally.