Advanced Applications of Nanotechnology in Laboratory Diagnostic Methods: A Comprehensive Overview

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Fahad Mesfer Alotaibi, Ahmad Mohammed Alomai, Mohammed Shafi Alanazi, Abdulwahab Saeed Alzahrani, Ahmed Abdurrazaq Hayjan, Hamsa Rabia Saad Alquatany, Sulaiman Ahmed Salem Alhassan, Basem Mohammed Mousa Safhi, Essa Mohamed Ahmed Kinani, Ahmed Ali Daghriri, Hussain Dyab Ahmed Hamzi, Abdu Hadi Hamoud Gharwi, Aishah Ali Ali Sharahili, Abdulmajeed Mohsen Ali Khawaji, Nader Munaji Abdu Suwayyid.

Abstract

Background: The rapid identification of infectious diseases is critical for improving public health outcomes and therapeutic efficacy. Traditional diagnostic methods often suffer from limitations in sensitivity and speed, necessitating the exploration of innovative approaches. This review focuses on the integration of nanotechnology in developing advanced diagnostic tools, emphasizing its potential to enhance detection accuracy and reduce costs.


Methods: A comprehensive analysis of various nanotechnology-based diagnostic techniques, including biosensors, immunoassays, and molecular diagnostics, is presented. Methods employed involve the synthesis of nanostructured materials and their application in biosensing platforms, highlighting their superior sensitivity and specificity.


Results: Results indicate that nanotechnology significantly improves the performance of diagnostic assays, enabling rapid and reliable disease detection. For instance, nanobiosensors demonstrate enhanced interaction with target biomarkers, leading to quicker diagnostic results compared to conventional methods.


Conclusions: The review concludes that the incorporation of nanotechnology into diagnostic practices not only streamlines the detection process but also has the potential to revolutionize point-of-care testing. Future research should focus on addressing the challenges associated with the practical application of nanodiagnostics in clinical settings, including regulatory considerations and safety assessments. Overall, the findings underscore the transformative impact of nanotechnology on the field of diagnostics, paving the way for more effective disease management strategies.


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