The Role of Deep Learning in Advancing Computer-Aided Diagnosis in Medical Imaging: A Comprehensive Review

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Naif Abdulaziz Alhamdan, Ahmad Salem Alenzi, Ghazi Shujan Ayed Alnefaie, Gaber Fatem Al Mutairi, Maged Dagheleb Alotaibi, Omar Hamed Alanazi, Abdullah Hadi Haddadi, Bassam Abdullah Alanazi, Abdulmalik Sulaiman Alkhames, Abdulaziz Mohammed Alotaibi, Ahmed A. Alhazim, Ali Majed Malhan, Salem Nasser Alotibi, Saad Mohammed Nasser Al-Baker, Ali Hussain Albasrawi.

Abstract

Background: Medical imaging is vital for diagnosing numerous health conditions, yet the increasing volume of imaging data presents significant challenges for radiologists. Traditional computer-aided diagnosis (CAD) systems have shown limited clinical implementation due to inadequate performance. The advent of deep learning technologies offers promising solutions to enhance imaging analysis and diagnostic accuracy.


Methods: This review examines the evolution and application of deep learning techniques in medical imaging, particularly in CAD systems. We analyze the transition from traditional machine learning to deep learning, highlighting methodologies such as deep convolutional neural networks (DCNNs) that enable automated feature extraction from complex imaging data. A comprehensive literature search was conducted to assess the performance of deep learning in various imaging modalities.


Results: The findings indicate that deep learning approaches, particularly DCNNs, significantly outperform traditional CAD systems by autonomously identifying and classifying pathological features in medical images. Studies demonstrate enhanced sensitivity and specificity in detecting malignancies, improving overall diagnostic accuracy. However, challenges remain regarding the integration of these technologies into clinical workflows, including the need for extensive training datasets and the potential for over-reliance on automated systems.


Conclusion: Deep learning represents a transformative advancement in the field of medical imaging and CAD. While promising results have been reported, further research is necessary to address existing barriers to clinical adoption. Standardization of performance metrics, rigorous testing across diverse populations, and comprehensive training for healthcare professionals are essential for the successful implementation of deep learning-based CAD systems in routine clinical practice.


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