Advancements in Vaccine Development: mRNA Technology Beyond COVID-19

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Nawaf Ali Atiah Khubrani, Muteeb Mohamed Alasiri, Sumayyah Hassan Salman Almalki, Salem Hammad Muslh, Meshal Saleh Alenazi, Lala Ahmed Yahya Alqawsi, Mohammed Yahya Sharahili, Ibrahim Mohamed Abdullah Robidi, Fatimah Abdrabalrasool Sukair, Reem Mohamed Bohumail, Wed Sulaiman Mohd Qunfuthi, Mohammadiah Ahmed Khader Magfoory, Majed Mohamed Hasan Abu Kaftah, Abdu Ali Yahya Oqaybi, Salma Yahya Hadi Haddadi.

Abstract

Background: The development of mRNA vaccines has changed the way vaccines are made, and the quick creation of COVID-19 vaccines is a good example of this. Traditional vaccines usually use viruses that have been killed or weakened. But mRNA vaccines use man-made genetic material to tell cells how to make antigens, which triggers a strong immune reaction. This new way of doing things has made it easier to fight many viral diseases and other health problems.


Aim: The main goal of this paper is to look at how far mRNA vaccine technology has come and how it might be used to treat other diseases, such as cancer, autoimmune disorders, and viruses.


Methods: A full review of all the recent literature on mRNA vaccines was done, looking at data from clinical trials, profiles of safety and effectiveness, and case studies. The study looked at studies that were reviewed by experts in the field, databases for clinical trials, and the latest developments in the field.


Results: The results show that mRNA vaccine research has come a long way, showing that it is more immunogenic and adaptable than traditional vaccines. Also, mRNA vaccines that target illnesses like flu, the Zika virus, and different types of cancer are showing promise in current clinical studies.


Conclusion: The progress made in mRNA technology represents a major shift in the way vaccines are made, opening the door for quick responses to new health threats. To get the most out of mRNA vaccines and open the door to new treatment approaches in public health, more study and funding must be put into this area.


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