Enhancing Molecular Diagnostics in Saudi Laboratories: Meeting Precision Medicine Demands for Vision 2030

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Waleed Dhawi Fahad AlDhafeery, Faiz Azbi Numan Almutairy, Ahmad Haloush Awadh Alenazi, Hamdi Ali Tabaan Alenazi, Fahad Ataih Alanazi, Munif Shuayl Fayadh Aldafeeri, Bander Ali Almutairy, Anud Jasir Sabih Alzafiri.

Abstract

Background: Saudi Arabia's Vision 2030 healthcare transformation emphasizes the critical role of precision medicine in improving patient outcomes and healthcare efficiency. Molecular diagnostics, a cornerstone of precision medicine, requires advanced laboratory capabilities and a skilled workforce. This comprehensive review examines the current state of molecular diagnostics in Saudi laboratories, identifies key challenges, and proposes strategies for enhancing capabilities to meet the precision medicine demands of Vision 2030.


Methods: A systematic literature review was conducted using PubMed, Scopus, and Web of Science databases. Studies published between 2010-2024 addressing molecular diagnostics in Saudi laboratories, precision medicine initiatives, and workforce development were included. Thematic analysis identified key challenges, opportunities, and strategic recommendations for enhancing molecular diagnostic capabilities.


Results: The review identified four major themes: (1) current state of molecular diagnostics in Saudi laboratories, (2) precision medicine initiatives and demands, (3) challenges in implementing advanced molecular diagnostics, and (4) strategies for enhancing laboratory capabilities and workforce development. Key challenges included technological infrastructure, workforce skills, quality assurance, and regulatory frameworks. Promising strategies involved investment in advanced technologies, specialized training programs, international collaborations, and policy reforms.


Conclusion: Enhancing molecular diagnostics in Saudi laboratories is crucial for meeting the precision medicine demands of Vision 2030. Overcoming challenges requires strategic investments in infrastructure, workforce development, and regulatory frameworks. Collaborative efforts among healthcare providers, policymakers, and academic institutions are essential for driving the necessary advancements. By prioritizing molecular diagnostics, Saudi Arabia can position itself at the forefront of precision medicine in the Middle East and globally.


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